Marvel Studios confirmed that the reboot of the 'Fantastic Four' will kickstart MCU's Phase 6 and will serve as the lead-up to 'Avengers: Secret Wars', but with a 'Nova' series rumored to be in development, there is also the possibility of 'Annihilation' being one of the major movies in the works. Then ideally the plot would revolve around Annihilus, the intergalactic supervillain who leads an armada of warships, setting off an annihilation wave that destroys planets. While some cosmic heroes such as Star-Lord and Drax (Both Guardians of the Galaxy at the moment) try and fend off the attack, they find an able ally in Nova, who stops the wave and ultimately kills Annihulus in the process.

The crossover series brings in several cosmic superheroes into the picture including the Silver Surfer and the Skrulls. The miniseries was written by Keith Giffen, with Andy Schmidt serving as the editor. With 'Nova' reported as one of the space series in development for Disney+, there's that possibility of the character being introduced in 'Guardians of the Galaxy Vol.3' that may also serve as the backdoor pilot for the much-awaited superhero.

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The alternate theory is the introduction of Galactus, who also fills in as the next big baddie that Marvel can look at after Thanos, but again, if it's a Nova origin story that Marvel is planning, then we may see Annihilus first. For those unfamiliar with Nova, the superhero is a member of the Nova Corps, with superhuman abilities including enhanced strength, flight, and resistance to injury and his origin story may see Richard Rider (Nova) battle Annihilus with some assistance from Guardians of the Galaxy, since most of the team have played key roles in taking on Annihilus in the comics.

But all this, of course, is pure speculation based on the comics, and Marvel is known to have tweaked storylines in the past. The latest update sees 'Moon Knight's Sabir Pirzada attached to the project, and should the news be confirmed in the D23 Expo in September, it's safe to assume that 'Nova' may perhaps tie into the 'Fantastic 4' movie and might also set up 'Annihilation' as the third bigger blockbuster after 'Secret Wars'. Annihilation will also serve as the first space crossover movie in the MCU.

'Infinity War' set the tone by bringing in the Guardians and Thor together and also puts them in a couple of adventures that were shown in 'Thor: Love and Thunder'. With the studios keen to introduce new characters in the mix, it makes sense to have a crossover involving the cosmic superheroes.